1
State Space
2
Operating with Vectors
3
Trajectories and Time Series
4
Models and Change Vectors
- 4.1 Introduction to Models and Change Equations: The Bathtub4.2 Models and Change Equations in 2 Dimensions: Shark Meets Tuna4.3 From Change Equations to Change Vectors4.4 State spaces and change vectors in 2D4.5 Trajectories in 2D4.6 Logistic Growth4.7 Models and Vectorfields: a nonlinear example in 1D4.8 Modeling Chemical Reactions4.9 Epidemiology4.10 Immune Dynamics
5
Euler's Method
7
Linear Stability Analysis
8
Higher Dimensions
9
The Lac operon: a biological switch
10
Bifurcation
12
The Central Dogma
13
Stable Oscillations in Science (and Music)
14
Oscillations in Physiology
16
Chaos 1
17
Chaos 2
19
Chaos 4
20
Chaos and Cardiology
21
Applications of Linear Algebra
The Central Dogma
Summary --- The “Central Dogma of Molecular Biology”
- The “Central Dogma of Molecular Biology”: What’s wrong with this picture? The work of Barbara McClintock on reverse transcription (Nobel Prize 1983).
- Positive feedback of protein on gene expression: the work of Monod, Jacob and Lwoff on the lac operon. (Nobel Prize 1965). The idea of a “biological switch”, and its relation to saddle-node bifurcation.
